04/05/2018 / By Ralph Flores
The anti-obesity effects of bitter melon seeds – in particular, its oil extracts – could be linked to changes in density in the hypothalamic spine, that is, the region connecting the hypothalamus and the spinal cord. The study, which was published in the Journal of Nutrition & Intermediary Metabolism, also stated that bitter melon seeds also affect the mammalian target of rapamycin (mTOR) pathway, which plays a role in protein synthesis.
Based on the findings, researchers posited that the plasticity of the hypothalamus could help the fat-reducing property of bitter melon seed oil.
Find the full text of the study at this link.
Journal Reference:
Xu Y, Xu L, Chen XT, Sun P, Guo Q, Wang HL. BITTER MELON SEED OIL MAY REDUCE THE ADIPOSITY THROUGH THE HYPOTHALAMUS MTOR SIGNALING IN MICE FED A HIGH FAT DIET. Journal of Nutrition & Intermediary Metabolism. December 2016;6:16–21. DOI: 10.1016/j.jnim.2016.04.003
Tagged Under: anti-obesity, bitter melon seed oil, brain function, central nervous system, hypothalamus, mTOR, obesity, S6, Spine density