05/15/2019 / By Michelle Simmons
Osteoporosis may be more likely to develop in women than in men, but that doesn’t mean men won’t have it. To treat androgen-deficient osteoporosis in men, researchers at the National University of Malaysia investigate the use of longjack (Eurycoma longifolia). In their study published in the Journal of Ayurveda and Integrative Medicine, they reported that longjack could be a natural alternative to conventional treatments used to address osteoporosis in men.
Also known as tongkat ali, longjack has attracted considerable interest because of its potential to stimulate bone formation in androgen-deficient osteoporosis. In the study, the researchers examined the effects of longjack on bone formation using an in vitro osteoblastic cell model. They compared longjack treatment with testosterone replacement, which is one of the standard treatments used for androgen-deficient osteoporosis.
The researchers found that treatment with longjack extract at a dose of 25 micrograms per milliliter (ug/mL) significantly increases cell growth, alkaline phosphatase activity, and collagen deposition and mineralization. They also looked into the mechanisms underlying the ability of longjack to stimulate bone formation. They did this by analyzing the expression of bone-related protein biomarkers and found that the expression of bone-related mediators was well-regulated in longjack-treated cell cultures compared with the control. These findings demonstrated the ability of longjack to improve bone development. (Related: Osteoporosis in men: Facts and recommendations the mainstream won’t tell you.)
Longjack is a plant native to Southeast Asian countries like Indonesia, Malaysia, and Thailand. It can be consumed in the form of dietary supplements, tea, energy drinks, or coffee, and it is used for the following:
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aging, alternative medicine, bone health, Bones, disease treatments, Eurycoma longifolia, herbal medicine, Herbs, longjack, men's health, natural cures, natural medicine, osteoporosis, remedies, research, therapies, tongkat ali
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