03/25/2020 / By Evangelyn Rodriguez
Researchers from The First Affiliated Hospital of Soochow University in China investigated the potential of a cannabinoid receptor 2 (CB2) agonist in preventing bone destruction and inflammation associated with collagen-induced arthritis (CIA) in mice. Their findings were published in the Journal of Bone and Mineral Research.
Based on these findings, the researchers concluded that JWH133 ameliorates bone destruction in CIA mice by inhibiting the generation of osteoclasts and modulating inflammatory responses. This mechanism of action highlights its potential in the treatment of rheumatoid arthritis.
Journal Reference:
Zhu M, Yu B, Bai J, Wang X, Guo X, Liu Y, Lin J, Hu S, Zhang W, Tao Y, et al. CANNABINOID RECEPTOR 2 AGONIST PREVENTS LOCAL AND SYSTEMIC INFLAMMATORY BONE DESTRUCTION IN RHEUMATOID ARTHRITIS. Journal of Bone and Mineral Research. 2019;34(4):739–751. DOI: 10.1002/jbmr.3637
Tagged Under:
anti-aging science, anti-inflammatory, arthritis cures, bone destruction, cannabinoid receptor 2, collagen-induced arthritis, immune system, inflammation, research, rheumatoid arthritis, selective agonist
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