Researchers examine role of micronutrients in atopic dermatitis

Researchers from the University of California, Davis and the University of Arizona conducted a systematic search to evaluate the role of oral micronutrients in atopic dermatitis (AD). Their review was published in The Journal of Alternative and Complementary Medicine.

• The pathophysiology of AD involves a complex interplay between immune system dysfunction, genetics and environmental factors.
• Because nutritional status influences immune function, scientists are wondering about the role of dietary factors in the pathogenesis of AD.
• While food allergies and elimination diets have been studied in atopy, the impact of vitamins, minerals and other micronutrients on the risk of AD and the severity of AD symptoms is yet to be explored.
• The researchers reviewed 49 different studies and discussed evidence of how various micronutrients, such as vitamins C, E and D and trace minerals like zinc, selenium, iron, copper, magnesium and strontium, are linked to AD. They also discussed how supplementation affects disease severity.
• The researchers reported that while vitamins C and E have no associations with AD, there is sufficient evidence suggesting vitamin D supplementation can provide benefits for people with AD.
• They also found that a deficiency of selenium and zinc could exacerbate AD.

The researchers concluded that certain oral micronutrients play a role in AD; however, current data is insufficient to confidently discern the role of other vitamins and trace minerals on AD.

Read the full study at this link.

Journal Reference:

Vaughn AR, Foolad N, Maarouf M, Tran KA, Shi VY. MICRONUTRIENTS IN ATOPIC DERMATITIS: A SYSTEMATIC REVIEW. The Journal of Alternative and Complementary Medicine. 04 June 2019;25(6):567–577. DOI: 10.1089/acm.2018.0363